A clever cartoon strip is here.
Thanks for posting it.
There would be a major difference between reality and science fiction is we actually did meed an alien race that evolved from lizards, like Klingons, or mole-like criters, like the Ferenghi.
First off their vocal abilities (if indeed they had any) would be vastly different.
Their languages would not be sort of difficult, like Klingon, but impossible, like talking to whales.
Odds are even that they would speak at a frequency we could not hear.
There were a couple of episodes of ST:TNG that got into this. The Crystalline entities which saw us as "ugly bags of mostly water", and the race that spoke in metaphors. "Chaka, when the walls fell".
Star Wars, being more infantile, assumes that everyone speaks some sort of English.